Who Should NOT Get Vaccinated with these Vaccines?
Because of age, health conditions, or other factors, some people
should not get certain vaccines or should wait before getting them.
Read the guidelines below for each vaccine.
Adenovirus
vaccine
Some people should not get adenovirus
vaccine.
- Anyone with a severe (life-threatening) allergy to any
component of the vaccine. Tell the doctor if you have any
severe allergies.
- Pregnant women or nursing mothers.
- Anyone who is unable to swallow the vaccine tablets whole
without chewing them.
- Anyone younger than 17 or older than 50 years of age.
A woman who learns she was pregnant when she got the vaccine, or
becomes pregnant within 6 weeks after vaccination, should contact
the Adenovirus Vaccine Pregnancy Registry at
1-866-790-4549. This will help us learn how pregnant women and
their babies respond to the vaccine.
Note: Adenovirus vaccine is approved for use
only among military personnel.
This information was taken directly from the Adenovirus
VIS
[PDF - 59 KB]
(This information taken from Adenovirus VIS dated 7/14/11. If the
actual VIS is more recent than this date, the information on this
page needs to be updated.)

Anthrax vaccine
Some people should not get anthrax vaccine.
- Anyone who has had a serious allergic reaction to a previous
dose of anthrax vaccine should not get another dose.
- Anyone who has a severe allergy to any vaccine component should
not get a dose. Tell your provider if you have any severe
allergies, including latex.
- If you have ever had Guillain Barré syndrome (GBS), your
provider might recommend not getting anthrax vaccine.
- If you have a moderate or severe illness your provider might
ask you to wait until you recover to get the vaccine. People with
mild illness can usually be vaccinated.
- Vaccination may be recommended for pregnant women who have been
exposed to anthrax and are at risk of developing inhalation
disease. Nursing mothers may safely be given anthrax
vaccine.
This information was taken directly from the Anthrax VIS
[PDF - 72 KB]
(This information taken from Anthrax VIS
dated 3/10/10. If the actual VIS is more recent than this date, the
information on this page needs to be updated.)

DTaP vaccine (Diphtheria, Tetanus,
& acellular Pertussis)
Some children should not get DTaP vaccine or should wait.
- Children with minor illnesses, such as a cold, may be
vaccinated. But children who are moderately or severely ill should
usually wait until they recover before getting DTaP vaccine.
- Any child who had a life-threatening allergic reaction after a
dose of DTaP should not get another dose.
- Any child who suffered a brain or nervous system disease within
7 days after a dose of DTaP should not get another dose.
- Talk with your doctor if your child:
- had a seizure or collapsed after a dose of DTaP
- cried non-stop for 3 hours or more after a dose of DTaP
- had a fever over 105 degrees Fahrenheit after a dose of
DTaP.
Ask your health care provider for more information. Some of
these children should not get another dose of pertussis vaccine,
but may get a vaccine without pertussis, called DT. DTaP should not
be given to anyone 7 years of age or older.
This information was taken directly from the DTaP VIS
[PDF - 59 KB]
(This information taken from DTaP VIS
dated 5/17/07. If the actual VIS is more recent than this date, the
information on this page needs to be updated.)

Hepatitis A vaccine
Some people should not get hepatitis A vaccine or should
wait.
- Anyone who has ever had a severe (life-threatening) allergic
reaction to a previous dose of hepatitis A vaccine should not get
another dose.
- Anyone who has a severe (life-threatening) allergy to any
vaccine component should not get the vaccine. Tell your
doctor if you have any severe allergies, including a
severe allergy to latex. All hepatitis A vaccines contain alum and
some hepatitis A vaccines contain 2-phenoxyethanol.
- Anyone who is moderately or severely ill at the time the shot
is scheduled should probably wait until they recover. Ask your
doctor. People with a mild illness can usually get the
vaccine.
- Tell your doctor if you are pregnant. Because hepatitis A
vaccine is inactivated (killed), the risk to a pregnant woman or
her unborn baby is believed to be very low. But your doctor can
weigh any theoretical risk from the vaccine against the need for
protection.
This information was taken directly from the Hepatitis A
VIS
[PDF - 79 KB]
(This information taken from Hepatitis A
VIS dated 10/25/11. If the actual VIS is more recent than this
date, the information on this page needs to be updated.)

Hepatitis B vaccine
Who should not get hepatitis B vaccine?
- Anyone with a life-threatening allergy to yeast, or to any
other component of the vaccine, should not get hepatitis B vaccine.
Tell your provider if you have any severe allergies.
- Anyone who has had a life-threatening allergic reaction to a
previous dose of hepatitis B vaccine should not get another
dose.
- Anyone who is moderately or severely ill when a dose of vaccine
is scheduled should probably wait until they recover before getting
the vaccine.
Your doctor can give you more information about these
precautions.
Note: You might be asked to wait 28 days before donating blood
after getting hepatitis B vaccine. This is because the screening
test could mistake vaccine in the bloodstream (which is not
infectious) for hepatitis B infection.
This information was taken directly from the Hepatitis B
VIS
[PDF - 166 KB]
(This information taken from Hepatitis B
VIS dated 2/2/12. If the actual VIS is more recent than this date,
the information on this page needs to be updated.)

Hib vaccine
Some people should not get Hib vaccine or should wait.
- People who have ever had a life-threatening allergic reaction
to a previous dose of Hib vaccine should not get another dose.
- Children less than 6 weeks of age should not get Hib
vaccine.
- People who are moderately or severely ill at the time the shot
is scheduled should usually wait until they recover before getting
Hib vaccine.
Ask your doctor or nurse for more information.
This information was taken directly from the Hib VIS
[PDF - 65 KB]
(This information taken from Hib VIS dated
12/16/98. If the actual VIS is more recent than this date, the
information on this page needs to be updated.)

HPV-Cervarix (Human Papillomavirus)
vaccine
Some people should not get HPV vaccine or should wait.
This information was taken directly from the HPV-Cervarix
VIS
[PDF - 37 KB]
(This information taken from HPV VIS dated
5/3/11. If the actual VIS is more recent than this date, the
information on this page needs to be updated.)

HPV-Gardasil (Human
Papillomavirus) vaccine
Some people should not get HPV vaccine or should wait.
This information was taken directly from the HPV-Gardasil
VIS
[PDF - 159 KB]
(This information taken from HPV VIS dated
2/22/12. If the actual VIS is more recent than this date, the
information on this page needs to be updated.)

Influenza (inactivated) vaccine
Some people should not get inactivated influenza vaccine
or should wait.
- Tell your doctor if you have any severe (lifethreatening)
allergies, including a severe allergy to eggs. A severe allergy to
any vaccine component may be a reason not to get the vaccine.
Allergic reactions to influenza vaccine are rare.
- Tell your doctor if you ever had a severe reaction after a dose
of influenza vaccine.
- Tell your doctor if you ever had Guillain-Barré Syndrome (a
severe paralytic illness, also called GBS). Your doctor will help
you decide whether the vaccine is recommended for you.
- People who are moderately or severely ill should usually wait
until they recover before getting flu vaccine. If you are ill, talk
to your doctor about whether to reschedule the vaccination. People
with a mild illness can usually get the vaccine.
This information was taken directly from the Inactivated
Influenza VIS
[PDF - 269 KB]
(This information taken from Inactivated
Influenza VIS dated 7/2/12. If the actual VIS is more recent than
this date, the information on this page needs to be
updated.)

Influenza (live) vaccine
Some people should not receive LAIV.
LAIV is not recommended for everyone. The following people
should get the inactivated vaccine (flu shot) instead:
- Adults 50 years of age and older or children from 6
months through 23 months of age. (Children younger than 6
months should not get either influenza vaccine.)
- Children younger than 5 years with asthma or one or more
episodes of wheezing within the past year.
- Pregnant women.
- People who have long-term health problems with:
- heart disease
- kidney or liver disease
- lung disease
- metabolic disease, such as diabetes
- asthma
- anemia, and other blood disorders
- Anyone with certain muscle or nerve disorders (such as seizure
disorders or cerebral palsy) that can lead to breathing or
swallowing problems.
- Anyone with a weakened immune system.
- Anyone in close contact with someone whose immune system is so
weak they require care in a protected environment (such as a bone
marrow transplant unit). Close contacts of other people with a
weakened immune system (such as those with HIV)
may receive LAIV. Healthcare personnel in neonatal
intensive care units or oncology clinics may receive
LAIV.
- Children or adolescents on long-term aspirin treatment.
Tell your doctor if you have any severe (life-threatening)
allergies, including a severe allergy to eggs. A severe allergy to
any vaccine component may be a reason not to get the vaccine.
Allergic reactions to influenza vaccine are rare.
Tell your doctor if you ever had a severe reaction after a dose
of influenza vaccine.
Tell your doctor if you ever had Guillain-Barré syndrome (a
severe paralytic illness also called GBS). Your doctor will help
you decide whether the vaccine is recommended for you.
Tell your doctor if you have gotten any other vaccines in the
past 4 weeks.
Anyone with a nasal condition serious enough to make breathing
difficult, such as a very stuffy nose, should get the flu shot
instead.
People who are moderately or severely ill should usually wait
until they recover before getting flu vaccine. If you are ill, talk
to your doctor about whether to reschedule the vaccination. People
with a mild illness can usually get the vaccine.
This information was taken directly from the Live Influenza
VIS
[PDF - 275 KB]
(This information taken from Live
Influenza VIS dated 7/2/12. If the actual VIS is more recent than
this date, the information on this page needs to be
updated.)

JE Ixiaro (Japanese Encephalitis)
vaccine
Some people should not get JE vaccine.
- Anyone who has ever had a life-threatening allergic reaction to
a previous dose of this JE vaccine should not get another
dose.
(Note: A different JE vaccine was available until early 2011. A
life-threatening reaction to that vaccine might not be a reason to
avoid the current vaccine. Ask your doctor.) - Anyone who has a life-threatening allergy to any vaccine
component should not get the vaccine. Tell your doctor if you have
any severe allergies.
- Pregnant women should generally not get JE vaccine. But if you
are pregnant, check with your doctor. It could be recommended under
certain circumstances.
If you will be traveling for fewer than 30 days, especially if
you will be staying in major urban areas, tell your doctor. You may
be at lower risk and not need the vaccine.
This information was taken directly from the Japanese
Encephalitis VIS
[PDF - 66 KB]
(This information taken from Japanese
Encephalitis VIS dated 12/7/11. If the actual VIS is more recent
than this date, the information on this page needs to be
updated.)

MMR (Measles, Mumps, and Rubella )
vaccine
Some people should not get MMR vaccine or should wait.
This information was taken directly from the MMR VIS
[PDF - 191 KB]
(This information taken from MMR VIS dated
4/20/12. If the actual VIS is more recent than this date, the
information on this page needs to be updated.)

MMRV (Measles, Mumps, Rubella, and
Varicella) vaccine
Children should not get MMRV vaccine if they:
- Have ever had a life-threatening allergic reaction to a
previous dose of MMRV vaccine, or to either MMR or varicella
vaccine.
- Have ever had a life-threatening allergic reaction to any
component of the vaccine, including gelatin or the antibiotic
neomycin. Tell the doctor if your child has any severe
allergies.
- Have HIV/AIDS, or another disease that affects the immune
system.
- Are being treated with drugs that affect the immune system,
including high doses of oral steroids for 2 weeks or longer.
- Have any kind of cancer.
- Are being treated for cancer with radiation or drugs.
Check with your doctor if the child:
- Has a history of seizures, or has a parent, brother or sister
with a history of seizures.
- Has a parent, brother or sister with a history of immune system
problems.
- Has ever had a low platelet count, or another blood
disorder.
- Recently had a transfusion or received other blood
products.
- Might be pregnant.
Children who are moderately or severely ill at the time the shot
is scheduled should usually wait until they recover before getting
MMRV vaccine. Children who are only mildly ill may usually get the
vaccine.
Ask your provider for more information.
This information was taken directly from the MMRV VIS
[PDF - 242 KB]
(This information taken from MMRV VIS
dated 5/21/10. If the actual VIS is more recent than this date, the
information on this page needs to be updated.)

Meningococcal vaccine
Some people should not get meningococcal vaccine or should
wait.
- Anyone who has ever had a severe (life-threatening) allergic
reaction to a previous dose of MCV4 or MPSV4 vaccine should not get
another dose of either vaccine.
- Anyone who has a severe (life-threatening) allergy to any
vaccine component should not get the vaccine. Tell your doctor
if you have any severe allergies.
- Anyone who is moderately or severely ill at the time the shot
is scheduled should probably wait until they recover. Ask your
doctor. People with a mild illness can usually get the
vaccine.
- Meningococcal vaccines may be given to pregnant women. MCV4 is
a fairly new vaccine and has not been studied in pregnant women as
much as MPSV4 has. It should be used only if clearly needed. The
manufacturers of MCV4 maintain pregnancy registries for women who
are vaccinated while pregnant.
Except for children with sickle cell disease or without a
working spleen, meningococcal vaccines may be given at the same
time as other vaccines.
This information was taken directly from the Meningococcal
VIS
[PDF - 78 KB]
(This information taken from Meningococcal
VIS dated 10/14/11. If the actual VIS is more recent than this
date, the information on this page needs to be updated.)

PCV13 (Pneumococcal Conjugate)
vaccine
Some children should not get PCV13 or should wait.
Children should not get PCV13 if they had a serious
(life-threatening) allergic reaction to a previous dose of this
vaccine, to PCV7, or to any vaccine containing diphtheria toxoid
(for example, DTaP).
Children who are known to have a severe allergy to ay component
of PCV7 or PCV13 should not get PCV13. Tell your healthcare
provider if your child has any severe allergies.
Children with minor illnesses, such as a cold, may be
vaccinated. But children who are moderately or severely ill should
usually wait until they recover before getting the vaccine.
This information was taken directly from the PCV13 VIS
[PDF - 54 KB]
(This information taken from PCV13 VIS
dated 4/16/10. If the actual VIS is more recent than this date, the
information on this page needs to be updated.)

PPV23 (Pneumococcal
Polysaccharide) vaccine
Some people should not get PPSV or should wait:
- Anyone who has had a life-threatening allergic reaction to PPSV
should not get another dose.
- Anyone who has a severe allergy to any component of a vaccine
should not get that vaccine. Tell your provider if you have any
severe allergies.
- Anyone who is moderately or severely ill when the shot is
scheduled may be asked to wait until they recover before getting
the vaccine. Someone with a mild illness can usually be
vaccinated.
- Although there is no evidence that PPSV is harmful to either a
pregnant woman or to her fetus, as a precaution, women with
conditions that put them at risk for pneumococcal disease should be
vaccinated before becoming pregnant, if possible.
This information was taken directly from the PPSV VIS
[PDF - 125 KB]
(This information taken from PPSV VIS
dated 10/6/09. If the actual VIS is more recent than this date, the
information on this page needs to be updated.)

Polio vaccine
Some people should not get IPV or should wait.
These people should not get IPV:
- Anyone with a life-threatening allergy to any component of IPV,
including the antibiotics neomycin, streptomycin or polymyxin B,
should not get polio vaccine. Tell your doctor if you have any
severe allergies.
- Anyone who has a severe allergic reaction to a polio shot
should not get another one.
These people should wait:
- Anyone who is moderately or severely ill at the time the shot
is scheduled should usually wait until they recover before getting
polio vaccine. People with minor illnesses, such as a cold, may be
vaccinated.
Ask your health care provider for more information.
This information was taken directly from the IPV VIS
[PDF - 68 KB]
(This information taken from IPV VIS dated
11/08/11. If the actual VIS is more recent than this date, the
information on this page needs to be updated.)

Rabies vaccine
Talk with a doctor before getting rabies vaccine if you:
- ever had a serious (life-threatening) allergic reaction to a
previous dose of rabies vaccine, or to any component of the
vaccine; tell your doctor if you have any severe allergies,
- have a weakened immune system because of:
- HIV/AIDS or another disease that affects the immune
system,
- treatment with drugs that affect the immune system, such as
steroids,
- cancer, or cancer treatment with radiation or drugs.
If you have a minor illness, such as a cold, you can be
vaccinated. If you are moderately or severely ill, you should
probably wait until you recover before getting a routine
(non-exposure) dose of rabies vaccine.
If you have been exposed to rabies virus, you
should get the vaccine regardless of any other illnesses you may
have.
This information was taken directly from the Rabies VIS
[PDF - 128 KB]
(This information taken from Rabies VIS
dated 10/6/09. If the actual VIS is more recent than this date, the
information on this page needs to be updated.)

Rotavirus vaccine
Some people should not get rotavirus vaccine or should
wait.
- A baby who has had a severe (life-threatening) allergic
reaction to a dose of rotavirus vaccine should not get another
dose. A baby who has a severe (life-threatening) allergy to any
component of rotavirus vaccine should not get the vaccine. Tell
your doctor if your baby has any severe allergies that you know of,
including a severe allergy to latex.
- Babies with severe combined immunodeficiency” (SCID) should not
get rotavirus vaccine.
- Babies with mild illnesses can usually get the vaccine. Babies
who are moderately or severely ill should probably wait until they
recover. This includes babies who have moderate or severe diarrhea
or vomiting. Ask your doctor or nurse.
- Check with your doctor if your baby’s immune system is weakened
because of:
- HIV/AIDS, or any other disease that affects the immune
system
- treatment with drugs such as long-term steroids
- cancer, or cancer treatment with radiation or drugs
- Tell your doctor if your baby has ever had intussusception, a
type of bowel blockage that is treated in a hospital.
This information was taken directly from the Rotavirus
VIS
[PDF - 113 KB]
(This information taken from Rotavirus VIS
dated 12/6/10. If the actual VIS is more recent than this date, the
information on this page needs to be updated.)
See also: MMWR, Addition
of Severe Combined Immunodeficiency as a Contraindication for
Administration of Rotavirus VaccinePosted June 2010

Shingles (Herpes Zoster)
vaccine
Some people should not get shingles vaccine or should
wait.
A person should not get shingles vaccine who:
- has ever had a life-threatening allergic reaction to gelatin,
the antibiotic neomycin, or any other component of shingles
vaccine. Tell your doctor if you have any severe allergies.
- has a weakened immune system because of current:
- AIDS or another disease that affects the immune system,
- treatment with drugs that affect the immune system, such as
prolonged use of high-dose steroids,
- cancer treatment such as radiation or chemotherapy,
- cancer affecting the bone marrow or lymphatic system, such as
leukemia or lymphoma.
- is pregnant, or might be pregnant. Women should not become
pregnant until at least 4 weeks after getting shingles
vaccines.
Someone with a minor acute illness, such as a cold, may be
vaccinated. But anyone with a moderate or severe acute illness
should usually wait until they recover before getting the vaccine.
This includes anyone with a temperature of 101.3° F or higher.
This information was taken directly from the Shingles
VIS
[PDF - 132 KB]
(This information taken from Shingles VIS
dated 10/6/09. If the actual VIS is more recent than this date, the
information on this page needs to be updated.)

Smallpox (Vaccinia) vaccine
This medication guide replaces the Smallpox VIS. It is to be
used before one receives the vaccination.
Medical Guide for vaccination with ACAM2000
[PDF - 85 KB]
(10/1/09)

Td (Adult Tetanus & Diphtheria)
vaccine AND
Tdap vaccine (Combined Tetanus, Diphtheria & Pertussis)
Some people should not be vaccinated or should wait.
- Anyone who has had a life-threatening allergic reaction after a
dose of any tetanus, diphtheria, or pertussis containing vaccine
should not get Td or Tdap.
- Anyone who has a severe allergy to any component of a vaccine
should not get that vaccine. Tell your doctor if the person getting
the vaccine has any severe allergies.
- Anyone who had a coma, or long or multiple seizures within 7
days after a dose of DTP or DTaP should not get Tdap, unless a
cause other than the vaccine was found. These people may get
Td.
- Talk to your doctor if the person getting either vaccine:
- has epilepsy or another nervous system problem,
- had severe swelling or severe pain after a previous dose of
DTP, DTaP, DT, Td, or Tdap vaccine, or
- has had Guillain Barré Syndrome (GBS).
Anyone who has a moderate or severe illness on the day the shot
is scheduled should usually wait until they recover before getting
Tdap or Td vaccine. A person with a mild illness or low fever can
usually be vaccinated.
This information was taken directly from the Td-Tdap VIS
[PDF - 208 KB]
(This information taken from Td-Tdap VIS
dated 1/24/12. If the actual VIS is more recent than this date, the
information on this page needs to be updated.)

Typhoid vaccine
Some people should not get typhoid vaccine or should
wait.
Inactivated Typhoid Vaccine (Shot)
- Should not be given to children younger than 2 years of
age.
- Anyone who has had a severe reaction to a previous dose of this
vaccine should not get another dose.
- Anyone who has a severe allergy to any component of this
vaccine should not get it. Tell your doctor if you have any severe
allergies.
- Anyone who is moderately or severely ill at the time the shot
is scheduled should usually wait until they recover before getting
the vaccine.
Live Typhoid Vaccine (Oral)
- Should not be given to children younger than 6 years of
age.
- Anyone who has had a severe reaction to a previous dose of this
vaccine should not get another dose.
- Anyone who has a severe allergy to any component of this
vaccine should not get it. Tell your doctor if you have any severe
allergies.
- Anyone who is moderately or severely ill at the time the
vaccine is scheduled should usually wait until they recover before
getting it. Tell your doctor if you have an illness involving
vomiting or diarrhea.
- Anyone whose immune system is weakened should not get this
vaccine. They should get the typhoid shot instead. This includes
anyone who:
- has HIV/AIDS or another disease that affects the immune
system,
- is being treated with drugs that affect the immune system, such
as steroids, for 2 weeks or longer,
- has any kind of cancer,
- is taking cancer treatment with radiation or drugs.
- Oral typhoid vaccine should not be given until at least 3 days
after taking antibiotics.
Ask your doctor or nurse for more information.
This information was taken directly from the Typhoid VIS
[PDF - 188 KB]
(This information taken from Typhoid VIS
dated 5/29/12. If the actual VIS is more recent than this date, the
information on this page needs to be updated.)

Varicella (chickenpox)
vaccine
Some people should not get chickenpox vaccine or should
wait.
- People should not get chickenpox vaccine if they have ever had
a life-threatening allergic reaction to a previous dose of
chickenpox vaccine or to gelatin or the antibiotic neomycin.
- People who are moderately or severely ill at the time the shot
is scheduled should usually wait until they recover before getting
chickenpox vaccine.
- Pregnant women should wait to get chickenpox vaccine until
after they have given birth. Women should not get pregnant for 1
month after getting chickenpox vaccine.
- Some people should check with their doctor about whether they
should get chickenpox vaccine, including anyone who:
- Has HIV/AIDS or another disease that affects the immune
system
- Is being treated with drugs that affect the immune system, such
as steroids, for 2 weeks or longer
- Has any kind of cancer
- Is getting cancer treatment with radiation or drugs
- People who recently had a transfusion or were given other blood
products should ask their doctor when they may get chickenpox
vaccine.
Ask your provider for more information.
This information was taken directly from the Varicella
VIS
[PDF - 59 KB]
(This information taken from Varicella VIS
dated 3/13/08. If the actual VIS is more recent than this date, the
information on this page needs to be updated.)

Yellow Fever vaccine
Who should not get the yellow fever vaccine?
- Anyone with a severe (life-threatening) allergy to any
component of the vaccine, including eggs, chicken proteins, or
gelatin, or who has had a severe allergic reaction to a previous
dose of yellow fever vaccine should not get yellow fever vaccine.
Tell your doctor if you have any severe allergies.
- Infants younger than 6 months of age should not get the
vaccine.
- Tell your doctor if:
- Adults 60 years of age and older who cannot avoid travel to a
yellow fever area should discuss vaccination with their doctor.
They might be at increased risk for severe problems following
vaccination.
- Infants 6 through 8 months of age, pregnant women, and nursing
mothers should avoid or postpone travel to an area where there is
risk of yellow fever. If travel cannot be avoided, discuss
vaccination with your doctor.
If you cannot get the vaccine for medical reasons but require
proof of yellow fever vaccination for travel, your doctor can give
you a waiver letter if he considers the risk
acceptably low. If you plan to use a waiver, you should also
contact the embassy of the countries you plan to visit for more
information.
This information was taken directly from the Yellow Fever VIS
[PDF - 64 KB]
(This information taken from Yellow Fever
VIS dated 3/30/11. If the actual VIS is more recent than this date,
the information on this page needs to be updated.)
Accessibility Note:
All .pdf links provided on this page are available in text-only
format for text reader devices on the main VIS page.